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Non-Small Cell Lung Cancer clinical trials in Santa Monica, CA
45 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Santa Monica (within about 30 miles). Open a study to see who can join and how to contact the study team.
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A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
RecruitingPhase 3
- Beverly Hills Cancer Center ( Site 0116), Beverly Hills · 6 mi away
A Study of ZW251 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- University of California Los Angeles - Cancer Care - Santa Monica (UCLA), Santa Monica
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
RecruitingPhase 3
- Tower Cancer Research Foundation, Beverly Hills · 6 mi away
- Cedars-Sinai Cancer - Tarzana, Tarzana · 11 mi away
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
RecruitingPhase 1/2
- UCLA - Santa Monica /ID# 271690, Santa Monica
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
RecruitingPhase 3
- Kaiser Permanente-Woodland Hills, Woodland Hills · 12 mi away
Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
RecruitingPhase 3
- Clinical Research Advisors, LLC, Beverly Hills · 6 mi away
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
RecruitingPhase 3
- Tower Cancer Research Foundation, Beverly Hills · 6 mi away
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
RecruitingPhase 1
- Santa Monica UCLA Medical Center & Orthopaedic Hospital, Santa Monica
- UCLA Hematology/Oncology - Santa Monica, Santa Monica
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
RecruitingPhase 3
- Beverly Hills Cancer Center, Beverly Hills · 6 mi away
A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
RecruitingPhase 1
- ALX Center 11, Santa Monica
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
RecruitingPhase 1
- Research Site, Santa Monica
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
RecruitingPhase 3
- Beverly Hills Cancer Center ( Site 0070), Beverly Hills · 6 mi away
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- UCLA Medical Center, Santa Monica
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
RecruitingPhase 1/2
- Precision NextGen Oncology, Beverly Hills · 6 mi away
A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Kivu Trial Site, Santa Monica
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
RecruitingPhase 3
- Research Site, Beverly Hills · 6 mi away
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
RecruitingPhase 3
- UCLA Hematology/Oncology - Santa Monica, Santa Monica
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
RecruitingPhase 1
- UCLA Santa Monica, Santa Monica
- Beverly Hills Cancer Center, Beverly Hills · 6 mi away
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
RecruitingPhase 3
- Research Site, Beverly Hills · 6 mi away
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
RecruitingPhase 3
- Clinical Study Site, Beverly Hills · 6 mi away
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
RecruitingPhase 3
- Sarcoma Oncology Center, Santa Monica
- University of California Los Angeles, Santa Monica
A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- UCLA, Santa Monica
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
RecruitingPhase 1
- UCLA Health - Santa Monica Cancer Care, Santa Monica
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
RecruitingPhase 3
- Research Site, Santa Monica
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
RecruitingPhase 1/2
- UCLA - David Geffen School of Medicine, Santa Monica
- Precision NextGen Oncology and Research Center, Beverly Hills · 6 mi away
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
RecruitingPhase 1
- University of California, Los Angeles (UCLA), Santa Monica
Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer
RecruitingPhase 1
- Cedars-Sinai Cancer at Beverly Hills (THO), Beverly Hills · 6 mi away
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
RecruitingPhase 1
- UCLA Healthcare Hematology-Oncology, Santa Monica
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
RecruitingPhase 1/2
- UCLA Hematology/Oncology - Santa Monica, Santa Monica
- Beverly Hills Cancer Center, Beverly Hills · 6 mi away
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
RecruitingPhase 1
- UCLA Department of Medicine - Hematology & Oncology, Santa Monica
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
RecruitingPhase 2
- Research Site, Santa Monica
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
RecruitingPhase 1
- Sarcoma Oncology Center, Santa Monica
- Precision NextGen Oncology and Research Center, Beverly Hills · 6 mi away
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
RecruitingPhase 2
- Tower Cancer Research Foundation, Beverly Hills · 6 mi away
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
RecruitingPhase 1
- UCLA Santa Monica Hematology Oncology, Santa Monica
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
RecruitingPhase 1/2
- UCLA, Santa Monica
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
RecruitingPhase 2/3
- Tower Cancer Research Foundation, Beverly Hills · 6 mi away
- Cedars-Sinai Cancer - Tarzana, Tarzana · 11 mi away
- Kaiser Permanente-Woodland Hills, Woodland Hills · 12 mi away
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
RecruitingPhase 2
- Tower Cancer Research Foundation, Beverly Hills · 6 mi away
- Cedars-Sinai Cancer - Tarzana, Tarzana · 11 mi away
A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma
RecruitingPhase 2
- Precision NextGen Oncology and Research Center, Beverly Hills · 6 mi away
A Study of DB-1310 in Advanced/Metastatic Solid Tumors
RecruitingPhase 1/2
- UCLA Hematology/Oncology - Santa Monica, Santa Monica
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- UCLA Hematology/Oncology - Santa Monica, Santa Monica
Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
Recruiting
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles · 4 mi away
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
RecruitingPhase 1/2
- Research Site 128, Santa Monica
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
RecruitingPhase 1/2
- Precision NextGen Oncology, Beverly Hills · 6 mi away
Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases
RecruitingPhase 1
- Beverly Hills Cancer Center, Beverly Hills · 6 mi away
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK112 in Patients With Non-Small Cell Lung Cancer
RecruitingPhase 1
- Precision NextGen Oncology, Beverly Hills · 6 mi away
Non-Small Cell Lung Cancer trials in other cities
- Houston, TX145 studies
- New York City, NY121 studies
- Arlington, VA104 studies
- Nashville, TN97 studies
- Boston, MA90 studies
- Los Angeles, CA87 studies
- St. Louis, MO73 studies
- Chicago, IL61 studies
- Baltimore, MD60 studies
- San Antonio, TX59 studies
- Columbus, OH57 studies
- Washington, DC55 studies
Other studies in Santa Monica
- Breast Cancer28 studies
- Colorectal Cancer23 studies
- Cancer (all types)22 studies
- Metastatic Cancer19 studies
- Lung Cancer15 studies
- Ovarian Cancer15 studies
- Prostate Cancer15 studies
- Head and Neck Squamous Cell Carcinoma13 studies
- Heart Failure11 studies
- Endometrial Cancer10 studies
- Stomach Cancer9 studies
- Pancreatic Cancer9 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.