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Non-Small Cell Lung Cancer clinical trials in Grand Rapids, MI

44 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Grand Rapids (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07388524

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • START - Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06784193

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START), Grand Rapids
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • START Midwest Cancer and Hematology Centers of W Michigan, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • BAMF Health, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 3, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Corewell Health - Butterworth Hospital, Grand Rapids
  • Corewell Health - Lemmen Holton Cancer Pavilion, Grand Rapids
  • Corewell Health - Research Specimen Processing Area, Grand Rapids
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

RecruitingPhase 2
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03191149

Pan-tumor MRD Study

RecruitingObservational study
  • The Cancer & Hematology Centers (CHC), Grand Rapids
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • BAMF Health, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • Cancer & Hematology Centers of Western Michigan, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • START | Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06914128

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • START - Midwest Cancer Research Center, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • The Cancer & Hematology Centers, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07361562

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

RecruitingPhase 1
  • The Cancer & Hematology Centers, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05985655

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START - Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

RecruitingPhase 1
  • BAMF Health, Grand Rapids
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07094204

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2
  • START, Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521

Non-Small Cell Lung Cancer trials in other cities

Other studies in Grand Rapids

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.