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Breast Cancer clinical trials in Harrisburg, PA

12 studies for Breast Cancer are looking for participants at sites in and around Harrisburg (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

RecruitingPhase 3
  • Univ of Pittsburg Med Ctr Pinnacle, Harrisburg
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Penn State Milton S. Hershey Medical Center, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Penn State Milton S. Hershey Medical Center, Hershey · 12 mi away
  • Lehigh Valley Health Network - Cedar Crest, Allen · 13 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

RecruitingPhase 2
  • Penn State Cancer Institute, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT04886531

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

RecruitingPhase 1/2
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT05455619

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • Penn State Hershey Medical Center, Hershey · 12 mi away
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

RecruitingObservational study
  • Penn State Health Medical Group - Andrews Patel, Harrisburg
  • Penn State Cancer Institute, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Harrisburg

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.