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Head and Neck Squamous Cell Carcinoma clinical trials in Louisville, KY

11 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Louisville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site#0111, Louisville
  • Site#0115, Louisville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • The James Graham Brown Cancer Center at University of Louisville, Louisville
  • UofL Health Medical Center Northeast, Louisville
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Norton Cancer Institute, Louisville
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • The James Graham Brown Cancer Center at University of Louisville, Louisville
  • UofL Health Medical Center Northeast, Louisville
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Norton Cancer Institute, Louisville
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • Baptist Health Floyd, New Albany · 4 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

RecruitingPhase 3
  • The James Graham Brown Cancer Center at University of Louisville, Louisville
  • UofL Health Medical Center Northeast, Louisville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07441681

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Norton Cancer Institute, Louisville
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

RecruitingPhase 1/2
  • Norton Cancer Institue Downtown, Louisville
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06747585

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 115, Louisville
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Louisville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.