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Kidney Cancer (Renal Cell Carcinoma) clinical trials in New York City, NY

27 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

RecruitingPhase 1
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • NEO-811 NYC Site, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07300241

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

RecruitingPhase 1/2
  • Laura and Isaac Perlmutter Cancer Center ( Site 5016), New York
  • Memorial Sloan Kettering Cancer Center ( Site 5002), New York
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT07049926

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #60, New York
  • Exelixis Clinical Site #6, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • NYU Langone Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center ( Site 0126), New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07489495

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07293351

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06863311

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • Manhattan Eye Ear and Throat Hospital, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

RecruitingPhase 1/2
  • Icahn School of Medicine at Mount Sinai, New York
  • Evelyn H. Lauder Breast and Imaging Center (BAIC), New York
  • Memorial Sloan Kettering Cancer Center - Main Campus, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07195916

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

RecruitingPhase 1/2
  • Tisch Cancer Institute (TCI), Icahn School of Medicine, New York
  • Columbia University, New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04977453

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Mount Sinai Chelsea, New York
  • Mount Sinai Hospital, New York
  • Manhattan Eye Ear and Throat Hospital, New York
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05837767

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • New York Cancer & Blood Specialists, New York
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07195682

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, New York
  • Xencor Investigative Site, New York
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

RecruitingPhase 1/2
  • NYU Langone Health Perlmutter Cancer Center, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University - The Trustees of Columbia University in the City of New York, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT03972657

A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT06835972

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • NYU Laura and Isaac Perlmutter Cancer Center - 34th Street /ID# 257869, New York
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

A Study of Cemiplimab and Fianlimab in People With Clear Cell Renal Cell Carcinoma

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT06699602

Decision Aid (DA) for Renal Patients

Recruiting
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Dec 2, 2025 · NCT05387863

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.