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Myelofibrosis clinical trials in New York City, NY

18 studies for Myelofibrosis are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

RecruitingPhase 1/2
  • Icahn School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04176198

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center, New York
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07623161

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

RecruitingPhase 2
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06661915

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Montefiore, New York
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

RecruitingPhase 1
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering, New York
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06343805

A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Icahn School of Medicine At Mount Sinai, New York
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07008118

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06773195

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
  • Mount Sinai School of Medicine, New York
  • Weill Cornell Medicine, New York
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07441694

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

RecruitingPhase 2
  • Ruttenberg Treatment Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • NewYork-Presbyterian/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT05835466

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

RecruitingPhase 2
  • GSK Investigational Site, New York
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06517875

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Icahn School of Medicine At Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06034002

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

RecruitingPhase 2
  • Weill Cornell Medicine NewYork-Presbyterian, New York
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT05980806

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT07362225

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

RecruitingPhase 2
  • Ruttenberg Treatment Center, New York
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT06541249

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

RecruitingPhase 3
  • ICAHN School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT06479135

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

RecruitingPhase 1
  • Columbia University, New York
Ages 18 and older · All sexes · Updated Apr 13, 2025 · NCT05423691

Myelofibrosis trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.