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Myelofibrosis clinical trials in Houston, TX

19 studies for Myelofibrosis are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

RecruitingPhase 3
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07357727

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT04176198

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

RecruitingPhase 1
  • The University of Texas, MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07469891

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

RecruitingPhase 2
  • MD Anderson Cancer Center, Houston
Ages 18 to 75 · All sexes · Updated Sep 16, 2026 · NCT06345495

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

RecruitingPhase 3
  • MD Anderson Cancer Center, Houston
  • The University of Utah-Huntsman Cancer Institute, Houston
  • LUMI Research, Houston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07623161

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07441694

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

RecruitingPhase 1/2
  • The University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT07128381

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

RecruitingPhase 2
  • GSK Investigational Site, Houston
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06517875

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06034002

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

RecruitingPhase 2
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT05980806

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Houston
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

RecruitingPhase 3
  • U.T. MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT06479135

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2025 · NCT05423691

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Feb 21, 2023 · NCT05280509

Myelofibrosis trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.