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Rectal Cancer clinical trials in Nashville, TN

9 studies for Rectal Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institue, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Tennessee Oncology, PLLC, Nashville
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

RecruitingPhase 1/2
  • GSK Investigational Site, Nashville
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

Recruiting
  • Vanderbilt University Medical Center, Nashville
Ages 22 to 75 · All sexes · Updated Aug 21, 2026 · NCT07429110

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

RecruitingPhase 3
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Rectal Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.