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Treatment-Resistant Depressive Disorder clinical trials in New York City, NY

8 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

RecruitingPhase 3
  • The Medical Research Network, LLC, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07716098

Biomarker-Guided Antidepressant Selection

RecruitingPhase 4
  • Weill Cornell Medicine, New York
Ages 18 to 70 · All sexes · Updated Sep 23, 2026 · NCT07680140

DBS for TRD With the Medtronic Percept PC

Recruiting
  • Icahn School of Medicine at Mount Sinai, Mount Sinai West, New York
Ages 25 to 70 · All sexes · Updated Sep 22, 2026 · NCT05773755

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Recruiting
  • Mount Sinai Hospital, New York
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • The Medical Research Network, LLC, New York
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Maintenance rTMS for Depression (Maitr-De)

Recruiting
  • Weill Cornell Medicine, New York
Ages 18 to 80 · All sexes · Updated Apr 29, 2026 · NCT06938841

Biomarker-guided rTMS for Treatment Resistant Depression

RecruitingPhase 3
  • Weill Cornell Medicine, New York
Ages 22 to 65 · All sexes · Updated Feb 25, 2026 · NCT04041479

Treatment-Resistant Depressive Disorder trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.