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Head and Neck Cancer clinical trials in North Carolina
14 studies for Head and Neck Cancer are looking for participants at sites in North Carolina.
Cities in North Carolina
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Duke University, Durham
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
- Site#0118, Durham
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990Distance-Based Exercise to Preserve Function and Prevent Disability
- Novant Health Cancer Institute - Kernersville, Kernersville
- Novant Health Cancer Institute - Mount Airy, Mount Airy
- Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884DESTINY-PANTUMOUR04
- Research Site, Durham
- Research Site, Wilson
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery
- Levine Cancer Institute, Charlotte
- Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06607406Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
- Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill, Chapel Hill
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06096038Effects of Infusion Timing on Treatment Response in Solid Tumors
- University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07630168Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
- Carolina BioOncology Institute, Huntersville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 6, 2026 · NCT04099290Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
- University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 3, 2026 · NCT07278557X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
- Levine Cancer Institute, Charlotte
- Duke University, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 30, 2026 · NCT04389281Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy
- Duke University Medical Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT05793151SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Chapel Hill
- Massive Bio SYNERGY-AI site, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
- Levine Cancer Institute, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.