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Genetics of Cardiovascular and Neuromuscular Disease

RecruitingObservational study

Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.

Who can join

All ages · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion Criteria:

* Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

About the study

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

What is being tested

Sponsor: University of Chicago · Participants: 2,000 · Started: 1996-09

Contact the study team

Official record on ClinicalTrials.gov — NCT00138931

Locations in the U.S.

IllinoisUniversity of Chicago, Chicago

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.