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Arthritis clinical trials recruiting in the U.S.
26 studies for Arthritis are recruiting participants at sites across the United States.
Arthritis can cause pain, swelling and stiffness in and around the joints. Learn about the different types of Arthritis and how they can affect you.
Cities with the most studies
- Washington, DC5 studies
- New York City, NY5 studies
- Houston, TX3 studies
- Chicago, IL3 studies
- Cedar Rapids, IA3 studies
- San Diego, CA3 studies
By state
- Arizona4 studies
- California7 studies
- Colorado3 studies
- Florida3 studies
- Georgia3 studies
- Illinois4 studies
- Indiana3 studies
- Iowa3 studies
- Maryland4 studies
- Massachusetts5 studies
- New Jersey3 studies
- New York5 studies
- North Carolina4 studies
- Pennsylvania5 studies
- South Carolina4 studies
- Tennessee3 studies
- Texas5 studies
- Washington3 studies
- Wisconsin3 studies
Recently updated studies
Natural History and Development of Spondyloarthritis
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 99 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT01422694Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
RecruitingObservational studyHealthy volunteers welcome
1 Day โ 100 Years ยท All sexes ยท Updated Sep 25, 2026 ยท NCT03510442A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07153471A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06916806Daily Knee Sleeve Use Versus No Use in Older Adults With Chronic Knee Pain
Recruiting
Ages 50 to 64 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07674901Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
Recruiting
Ages 40 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07804446Study of Alkaptonuria
RecruitingObservational study
Ages 2 to 115 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT00005909Studies of the Natural History of Rheumatic Diseases
RecruitingObservational study
Ages 18 to 100 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT00024479Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
RecruitingObservational study
Up to age 21 ยท All sexes ยท Updated Aug 27, 2026 ยท NCT02418442Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty
Recruiting
Ages 45 and older ยท All sexes ยท Updated Aug 13, 2026 ยท NCT03921944Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders
Recruiting
Ages 18 to 100 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07180537A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
RecruitingObservational study
Ages 18 to 80 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07199738Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
RecruitingHealthy volunteers welcome
Ages 18 to 85 ยท All sexes ยท Updated Jun 12, 2026 ยท NCT05796908Impact of Biophoton Therapy on Chronic Severe Arthritis Pain
Recruiting
Ages 18 to 80 ยท All sexes ยท Updated May 22, 2026 ยท NCT06915012A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Apr 13, 2026 ยท NCT06647134Expanding Exercise Programming for Veterans Through Telehealth
Recruiting
Ages 18 and older ยท All sexes ยท Updated Apr 8, 2026 ยท NCT05666167Osteochondral Allograft in the Surgical Treatment of Basal Joint Arthritis
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Apr 8, 2026 ยท NCT03722537Dose Response of Exercise for Arthritis Management
Recruiting
Ages 18 and older ยท All sexes ยท Updated Apr 3, 2026 ยท NCT06880653Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Mar 11, 2026 ยท NCT05658575Ultralow Dose PET Imaging for 18F-NaF Uptake
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 120 ยท All sexes ยท Updated Dec 16, 2025 ยท NCT07284563The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 ยท All sexes ยท Updated Sep 23, 2025 ยท NCT05067998Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 19, 2025 ยท NCT05754190Embo Registry; National Registry for Artery Embolization
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2024 ยท NCT06477965Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis
Recruiting
Ages 18 to 90 ยท All sexes ยท Updated Oct 1, 2024 ยท NCT04238143Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
RecruitingPhase 1
Ages 20 and older ยท All sexes ยท Updated Apr 11, 2024 ยท NCT06361485From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.