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Early Rheumatoid Arthritis Lung Disease Study

RecruitingObservational study

Who can join

Ages 19 to 90 · All sexes

Full eligibility criteria
Inclusion Criteria:

* 19-90 years of age
* Able to give informed consent
* Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years

Exclusion Criteria:

* Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
* Pregnant

About the study

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.

Sponsor: University of Nebraska · Participants: 125 · Started: Mar 31, 2017

Contact the study team

Official record on ClinicalTrials.gov — NCT03192267

Locations in the U.S.

NebraskaUniversity of Nebraska Medical Center, Omaha

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.