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Biologics And Clinical Immunology Cohort at Sinai

RecruitingObservational study

Who can join

Ages 12 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Age 12 years and up.
* Able to provide informed consent.
* Medical care at Mount Sinai.
* Receiving a biologic medication or immune modulator at Mount Sinai, or considered an appropriate negative control or comparison participant by the study team.

About the study

The study team plans to establish a bioregistry of patients receiving biologic therapy as part of their standard treatment at the Mount Sinai Therapeutic Infusion Center and affiliated practices. The study team will to apply state-of-the-art approaches to assessing and predicting immunological and clinical responses associated with these standards and prescribed treatments. The approach is twofold. The first component is to establish a robust and flexible biorepository and database that includes demographic, immunologic, exposure and clinical records, and can facilitate research across disciplines, and across other registries affiliated with Mount Sinai. The second component is to address specific key research questions focused on using novel diagnostics to increase the effectiveness of biologic treatment. Most patients will be recruited from the Mount Sinai Therapeutic Infusion Center (TIC), although others receiving infusions elsewhere or at home will be recruited from outpatient Sinai affiliated clinical practices.

Sponsor: Icahn School of Medicine at Mount Sinai · Participants: 800 · Started: Mar 3, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT04784364

Locations in the U.S.

New YorkMount Sinai, New York

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.