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Cognitive Remediation Intervention to Prepare for Transition of Care

RecruitingPhase 2

The Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) Intervention: A Randomized Controlled Trial for Adolescents With Sickle Cell Disease to Prepare for Transition of Care

Who can join

Ages 10 to 18 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Diagnosis of SCD (all genotypes)
* Active follow-up at Children's of Alabama Hospital
* Ages 10-18
* English-speaking

Exclusion Criteria:

* History of seizures or overt stroke
* History of Intellectual Disability or Autism Spectrum Disorder
* Inability to participate in the MRI scan, such as metal implants, neurostimulators, claustrophobia
* Currently on psychotropic medications

About the study

Randomized Controlled Trial (RTC) testing the efficacy of a telehealth adaptation of the Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) intervention to prepare adolescents with sickle cell disease for transition of care.

What is being tested

Sponsor: University of Alabama at Birmingham · Participants: 120 · Started: Jul 1, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05336201

Locations in the U.S.

AlabamaUniversity of Alabama at Birmingham, Birmingham

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.