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South Asians and Coronary Plaque Registry
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Males and Females: Age 18 years or above * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh) * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers) * Sampling Method: Probability Sample Exclusion Criteria: * Under the age of 18 years * Unable to give informed consent * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min * Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker * Body mass index (BMI) of 35 or greater * Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast * Anyone who cannot do CCTA for any reason * Pregnancy
About the study
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.
What is being tested
- Coronary CT Angiogram (diagnostic test)
Sponsor: University of Texas Southwestern Medical Center · Participants: 300 · Started: Jun 15, 2022
Contact the study team
- Destiny Jones · Phone: 214.645.2049
- Anand Rohatgi · Phone: 214.645.7500
Official record on ClinicalTrials.gov — NCT05367297
Locations in the U.S.
| Texas | University of Texas Southwestern Medical Center, Dallas |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.