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Patient-driven Management of BP in CKD
Pharmacist-guided, Patient-driven Management of High Blood Pressure in CKD: A Novel Approach
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age \>= 18 years, * CKD stage 3 or 4 (estimated GFR: 15-59 mL/min/1.73m2) or * Stage 2 CKD (estimated GFR 60-89 mL/min/1.73m2) with urinary albumin/creatinine ratio (ACR 300 mg/g if no DM and 30 mg/g if with DM), and * Uncontrolled hypertension defined as the avg of 2 readings \> 140 systolic. Exclusion Criteria: * Severely uncontrolled hypertension defined as systolic BP \>180, * Patients with resistant hypertension and taking 4 BP medications, * Orthostatic hypotension defined as reduced systolic BP by 20 mmHg or diastolic BP by 10 mmHg after 3 minutes of standing, * Severe CKD defined as estimated GFR \< 20 mL/min/1.73m2, * Life expectancy \<1 year, * Severe liver disease, * Severe congestive heart failure, * Severe cognitive decline due to dementia, * Pregnant, breastfeeding, or unwilling to use adequate birth control
About the study
The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implementation of the self-management approach.
What is being tested
- Self-management of BP medications (behavioral)
- Self-monitoring of home BP (behavioral)
Sponsor: VA Office of Research and Development · Participants: 160 · Started: Dec 15, 2022
Contact the study team
- Diana Jalal, MD · Phone: (319) 338-0581
- Katharine M Geasland, RN · Phone: (319) 353-6318
Official record on ClinicalTrials.gov — NCT05546099
Locations in the U.S.
| Iowa | Iowa City VA Health Care System, Iowa City, IA, Iowa City |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.