Home › Ischemic Stroke › NCT05556395

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent

Exclusion Criteria:

* Inability to perform telephone-based cognitive assessments

About the study

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Sponsor: Johns Hopkins University · Participants: 150 · Started: Apr 1, 2022

Contact the study team

• Diane Echavarria · Phone: 410 502 5355

Official record on ClinicalTrials.gov — NCT05556395

Locations in the U.S.

Conditions

• Ischemic Stroke
• Dementia
• Alzheimer's Disease
• Stroke

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.