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A Precision Medicine Approach to Target Engagement for Emotion Regulation
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Elevated emotion dysregulation Exclusion Criteria: * Lack of proficiency in English * No access to smartphone * Conditions requiring greater than outpatient care
About the study
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.
What is being tested
- Checking the Facts (behavioral)
- Opposite to Emotion Action (behavioral)
- Mindfulness of Current Emotions (behavioral)
Sponsor: Matthew Southward, PhD · Participants: 390 · Started: Sep 29, 2023
Contact the study team
- Matthew W Southward, Ph.D. · Phone: 614-247-0331
Official record on ClinicalTrials.gov — NCT05651295
Locations in the U.S.
| Ohio | Ohio State University, Columbus |
Conditions
- Depression
- Anxiety
- Borderline Personality Disorder
- Obsessive-Compulsive Disorder
- Post-Traumatic Stress Disorder
- Eating Disorders
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.