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Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

Recruiting

Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

Patient participants in the RCT must be 18 or older; receive OUD treatment as part of the telemedicine program; and exhibit polysubstance use within the past three-months (i.e., use of one or more non-prescribed substances (excluding opioids and/or tobacco) by urine toxicology or self-report.

Exclusion Criteria:

* Demonstrating active, unstable or untreated psychiatric symptoms, including mania and/or psychosis that would interfere with study participation
* Inability to understand the study and provide informed consent in English

About the study

The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) and reduce polysubstance use among patients with OUD and polysubstance use in underserved areas. The intervention is based on behavioral activation (BA) and is specifically designed to be implemented by a trained peer recovery specialist. In this hybrid, Type-1 effectiveness-implementation randomized controlled trial (RCT), the investigators will evaluate the effectiveness and implementation of Peer Activate vs. treatment as usual (TAU) over twelve months.

What is being tested

Peer-Delivered Behavioral Activation ("Peer Activate") (behavioral)

Sponsor: University of Maryland, College Park · Participants: 160 · Started: Jun 15, 2023

Contact the study team

Morgan S Anvari, BA · Phone: 3014055095

Official record on ClinicalTrials.gov — NCT05973838

Locations in the U.S.

District of Columbia	HIPS Clinic, Washington D.C. (Not yet recruiting)
Maryland	University of Maryland Baltimore (UMD Drug Treatment Center), Baltimore (Not yet recruiting) University of Maryland, College Park, College Park (Not yet recruiting) Caroline County Behavioral Health, Denton

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.