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Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

PLANET: Exploring the Role of Plastics and Toxins in Intestinal Inflammation

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* The ability to sign and date an informed consent form
* Be pregnant, or wishing to become pregnant in the near future and enroll the infant that the individual is pregnant with
* Aged 18 or older
* English-speaking (this observational study uses non-validated questionnaires that are only available in English)
* Of any ethnicity
* Be a spouse, related household member (sibling, parent, etc.) or a child of an enrolled pregnant person

Exclusion Criteria:

* Individuals who are unable to give informed consent
* Be diagnosed with a pregnancy complication, such as intrauterine fetal demise/stillbirth, preeclampsia, hyperemesis gravidarum, or have an active infection, including chorioamnionitis or sepsis.

About the study

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as other diseases. With this information, the researchers hope to characterize better the role of environmental pollutants on IBD and develop novel strategies towards prevention.

Sponsor: Icahn School of Medicine at Mount Sinai · Participants: 46 · Started: Aug 15, 2023

Contact the study team

• Mellissa Picker, BS · Phone: 212-659-6710

Official record on ClinicalTrials.gov — NCT06001450

Locations in the U.S.

Conditions

• Crohn's Disease
• Inflammatory Bowel Disease

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.