Home › Post-Traumatic Stress Disorder › NCT06285708
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Current diagnosis of PTSD or subthreshold PTSD; ability to speak and understand the English language; and ability to complete the informed consent process. Exclusion Criteria: * Substance use disorder requiring medical management; imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment; and impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania).
About the study
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared to treatment as usual. However, no studies to date have assessed their effectiveness when used in combination. In light of this knowledge gap, the primary objective of this study will be to test the effectiveness of PE augmented with CRP as compared to PE with care as usual (self-guided treatment plan), an active comparator, for the reduction of suicide ideations and attempts for individuals with comorbid PTSD.
What is being tested
- Prolonged exposure (behavioral)
Sponsor: Ohio State University · Participants: 100 · Started: Feb 26, 2024
Contact the study team
- Jaryd Hiser, Ph.D. · Phone: 614-814-0163
Official record on ClinicalTrials.gov — NCT06285708
Locations in the U.S.
| Ohio | The Ohio State University, Columbus |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.