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Predictors of Post-COVID-19 Clinical and Cognitive Consequences
Predictors of Post-COVID Clinical and Cognitive Consequences
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * All individuals 18 years or older, with prior history of COVID-19 infection diagnosis * Both genders including all racial and ethnic groups * Patients with OSA (apnea hypopnea index of 5/hour on polysomnography) with history of COVID-19 infection will be eligible with prior history of COVID-19 infection and without COVID-19 for Aim 2 Exclusion Criteria: * Inability to give consent * Active suicidal symptoms * Children of all ages * Pregnant women
About the study
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.
Sponsor: VA Office of Research and Development · Participants: 200 · Started: Jan 19, 2023
Contact the study team
- Ruchi Rastogi, MS · Phone: (313) 576-4464
Official record on ClinicalTrials.gov — NCT06291870
Locations in the U.S.
| Michigan | John D. Dingell VA Medical Center, Detroit, MI, Detroit |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.