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VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

Recruiting

Can Virtual Reality Improve Patient Tolerance in Patients Undergoing Water Cooled Genicular Nerve Radio Frequency Ablation in Patients With Chronic Knee Pain? A Randomized Controlled Trial

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients undergoing genicular RFA will be eligible for inclusion in the study
* Patients with knee pain, baseline average of \> 4/10
* X-ray evidence of osteoarthritis of the knee
* Pain duration of \>6 weeks and no previous knee surgeries
* Patients will also only be included who have never undergone a RFA on the affected knee

Exclusion Criteria:

* Individuals who do not have evidence of osteoarthritis on X-ray,
* Secondary gain expected to influence treatment outcomes
* Poorly controlled psychiatric condition that could affect outcome (e.g. active substance abuse) or impose a barrier to participation
* Chronic opioid use and anticoagulation therapy that cannot be stopped and could warrant a different treatment approach (e.g. phenol ablation)
* Severe motion sickness
* Seizure disorder
* Vision loss
* Pregnant
* Nursing

About the study

This study will examine the impact of virtual reality used in conjunction with sedation compared to sedation alone in patients undergoing watervcooled genicular nerve ablations for chronic knee pain.

The goals of the study is to determine the relative efficacy of virtual reality as a distraction modality when used as an adjuvant to procedural sedation compared to sedation alone for procedure related pain. To assess procedural satisfaction, and 1-month pain and functional outcomes.To explore whether virtual reality and lower procedure-related pain scores affect 1-month outcomes. And finally to determine whether demographic and clinical characteristics are associated with outcome measures.

What is being tested

Sponsor: Northwestern University · Participants: 62 · Started: Jan 12, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06336447

Locations in the U.S.

IllinoisNorthwestern Medicine Pain Center, Chicago

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.