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Raman Spectroscopy and Skin Cancer

Pilot Study of Raman Spectroscopic Imaging for Skin Cancer

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Histologically confirmed skin cancer (either basal cell carcinoma or squamous cell carcinoma)
* Participants must plan to receive brachytherapy treatment for the skin cancer at the study site.
* Ability to provide consent to the study.

Exclusion Criteria:

* Patient belongs to a vulnerable population (Minors (under 18 years old), Adults unable to consent, prisoners).
* Lesions on the eyelid or in close proximity to the eye
* Pregnant women, or women of childbearing age who refuse pregnancy testing.
* Patient has pacemaker.

About the study

The goal of this observational study is to find out if Raman Spectroscopy, a type of imaging, can be used to determine the size of skin cancer tumors. The main question it aims to answer is:

-Can Raman Spectroscopy help figure out how far a tumor spreads?

This study will take measurements using laser light from an experimental, handheld probe by lightly touching the skin.

What is being tested

• Raman Spectroscopy handheld probe (EmVision, FL, USA) (device)
• Raman Spectroscopy laser source (Hubner Photonics Inc, CA, USA) (device)

Sponsor: Tiezhi Zhang · Participants: 20 · Started: Feb 13, 2025

Contact the study team

• Tiezhi Zhang · Phone: 631-444-3617

Official record on ClinicalTrials.gov — NCT06384924

Locations in the U.S.

Conditions

• Skin Cancer
• Basal Cell Carcinoma
• Squamous Cell Carcinoma

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.