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The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

Positive for any one or more of the following:

* All individuals aged above 18 years positive for habits (smoking and smokeless tobacco, chewing betel leaf, areca nut, paan masala, and/or regular use of alcohol)
* Clinical signs/symptoms (non-healing ulcers, white/ red/red \& white patches in the mouth, restriction of mouth opening and swelling of the neck)
* All individuals aged above 40 irrespective of habit/oral lesions

Exclusion Criteria:

* Individuals already diagnosed with oral cancer and undergoing treatment for oral cancer
* Under treatment for tuberculosis or suffering from any acute illness/ debilitating systemic disorders

About the study

Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers. This program is inclusive of long term surveillance to downstage oral cancer in India

What is being tested

• mHealth (diagnostic test)

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 5,122 · Started: Jul 30, 2024

Contact the study team

• Milind Rajadhyaksha, PhD · Phone: 646-608-2364
• Aditi Sahu · Phone: 646-608-1935

Official record on ClinicalTrials.gov — NCT06535867

Locations in the U.S.

Conditions

• Smoking and Youth
• Smoking
• Alcohol

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.