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The Collaborative Care PrTNER Study

RecruitingHealthy volunteers welcome

The Collaborative Care PrTNER (Prevention, Treatment, Navigation, Engagement, Resource) Project

Who can join

Ages 15 to 29 · Men · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

Aim 1:

* 15-24 years old;
* Cisgender male;
* History of condomless sex;
* Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2,
* Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
* Able to read and write in English

Aim 2:

* 15-29 years old;
* Cisgender male;
* Living with a diagnosis of HIV;
* CRAFFT score ≥2,
* Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
* Able to read and write in English

Aim 3

• All randomized study participants will be included in Aim 3.

Exclusion Criteria:

Aim 2:

* Participants will be excluded if they are:
* Assigned female sex at birth
* Identify as transgender
* Outside the age criteria (\<15 or \>29 years old)
* Cognitively unable to complete study requirements
* Living outside of the two geographic areas
* Do not screen positive for SU
* No prior substance use history
* No prior condomless sex;
* Unable to read or write in English,
* Plan to move in the next 12 months.

About the study

A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among young aged 15 to 29 through engagement in SU treatment.

What is being tested

Sponsor: Children's Hospital of Philadelphia · Participants: 275 · Started: Jan 2, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06585631

Locations in the U.S.

MarylandJohns Hopkins Center for Adolescent and Young Adult Health, Baltimore (Not yet recruiting)
PennsylvaniaChildren's Hospital of Philadelphia, Philadelphia

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.