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SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

Who can join

Ages 12 to 100 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Eligible participants must identify as Hispanic/Latino/a/x/e,
* be a first generation immigrant parent or parental figure (Parent)
* have a child (Youth) aged 12-17
* speak English and/or Spanish

Exclusion Criteria:

* Families planning to move within two years will be excluded

About the study

This study aims to prevent syndemic health conditions by decreasing acculturative stress and promoting resilience via SER Familia (Salud, Estrés y Resilencia en Familias/ Health, Stress, and Resilience in Families), a family-based intervention. SER Familia is a six-session intervention co-developed and delivered by community health workers (CHWs) that uses strategies to reduce acculturative stress, promote resilience, improve parent-child and family level health, while simultaneously helping families maintain strong social networks and better navigate community resources to address social determinants of health (SDOH). More specifically, investigators aim to: 1) Examine the efficacy of SER Familia to prevent or reduce the syndemic comprised of substance abuse, IPV, HIV risk, depression, and anxiety among Parents and Youth; and 2) Identify how individual, family, and community mechanisms of change related to acculturative stress and resilience mediates the effect of SER Familia.

What is being tested

• SER Familia (behavioral)

Sponsor: Duke University · Participants: 400 · Started: Jun 30, 2025

Contact the study team

• Rosa Gonzalez-Guarda, PhD · Phone: 9196132634
• Norma Garcia-Ortiz, BS · Phone: 9196849331

Official record on ClinicalTrials.gov — NCT06627764

Locations in the U.S.

Conditions

• Drug Use and Addiction
• HIV
• Depression
• Anxiety

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.