Home › Quitting Smoking › NCT06948058
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
Recruiting
Who can join
Ages 21 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * body mass index (BMI) ≥ 30 kg/m2 (i.e., obese) * smoked ≥ 5 cigarettes/day during the past year * 21 or older (due to minimum legal age EC restrictions) * exhaled breath carbon monoxide (CO) level \> 6 ppm at Baseline (BL) (to confirm self-reported smoking) * willing to use EC or NRT for 8 weeks * access to a Bluetooth-enabled smartphone/tablet (to permit remote measurement of CO and other outcome variables) Exclusion Criteria: * received smoking cessation treatment of any kind in the past 30 days (actively quitting smoking), * currently using EC or NRT more than 2 days/week (this may affect responses to study-supplied products) * hospitalized for mental illness in past 30 days * heart-related event (e.g., heart attack, severe angina) in past 30 days * residing with another person currently enrolled in the study * pregnant, nursing, or planning to become pregnant in the next 6 months * medical contraindication for study or product use (e.g., allergy to adhesives) * taken prescription weight loss medication in the last 30 days
About the study
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
What is being tested
- Electronic Cigarettes (EC) (other)
- Nicotine replacement therapy (NRT) (other)
Sponsor: Brown University · Participants: 60 · Started: Apr 1, 2025
Contact the study team
- CRESCENT Study Research Staff · Phone: 401-203-5339
Official record on ClinicalTrials.gov — NCT06948058
Locations in the U.S.
| Rhode Island | Brown University, Providence |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.