Home › Congenital Heart Defects › NCT06952933
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Congenital heart disease diagnosis, age \>= 18 years * Enrolled in CHI registry * English proficiency for survey completion * Access to an internet connection. Can be via computer or handheld device. Exclusion Criteria: * Any who opt out * Age \< 18 years * No diagnosis of congenital heart disease * Not enrolled in CHI registry/unable to access Internet
About the study
The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for exposures during a lifetime with congenital heart disease that may be associated with higher likelihood of developing PTSD.
Primary aim:
\- Identify individual patient characteristics (medical, psychosocial, socioeconomic, etc.) that are associated with a diagnosis of PTSD.
Secondary aims:
* Calculate the prevalence of those meeting PTSD criteria in the ACHD population using the "gold standard" diagnostic clinician interview, while using the same data to validate a PTSD screening self-report survey in the ACHD population. * Determine the role of resilience in ACHD patients using a validated screening survey to assess its protective role toward PTSD.
Hypotheses:
* There are certain exposures (e.g. post-surgical pain, ICU delirium, bullying due to CHD) that are associated with a higher incidence and odds of meeting PTSD criteria. * "Gold standard" diagnostic interviews will most accurately estimate the prevalence of PTSD in ACHD which has been overestimated on prior screening-based studies, although the scope of the problem is still great. * Patients with a higher resilience score will show an association with a lower risk of PTSD.
What is being tested
- Other (behavioral)
Sponsor: Dartmouth-Hitchcock Medical Center · Participants: 1,000 · Started: Sep 1, 2025
Contact the study team
- David J Harrison, MD · Phone: 603-650-5724
Official record on ClinicalTrials.gov — NCT06952933
Locations in the U.S.
| District of Columbia | Children's National Medical Center, Washington D.C. (Not yet recruiting) |
| New Hampshire | Dartmouth Hitchcock Medical Center, Lebanon |
| Ohio | Nationwide Children's Hospital, Columbus (Not yet recruiting) |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.