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Community-based Approach to Lowering Stress Through Mindfulness
Addressing Depression for African American Adults With Hypertension: Applying Community-Engaged Implementation Science
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * ≥18 years old * Lives, works, or spends much of their time in the South Side of Chicago neighborhood * Self-reports diagnosis of hypertension or high blood pressure by a clinician * Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10 * Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported Exclusion Criteria: * \<18 years old * Severe mental illness (e.g., bipolar disorder, psychosis) * Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt * Unable to provide informed consent or complete study activities in English
About the study
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:
* Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms? * Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control? * Is the intervention acceptable, appropriate, and feasible as delivered in a community setting?
Participants will:
* Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation. * Complete surveys online * Have their blood pressure measured with a non-invasive blood pressure cuff * Attend 1 focus group (optional)
What is being tested
- Mindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study) (behavioral)
Sponsor: Northwestern University · Participants: 60 · Started: Sep 10, 2025
Contact the study team
- Asia Ellis, BA · Phone: 13125033569
Official record on ClinicalTrials.gov — NCT06987799
Locations in the U.S.
| Illinois | The Salvation Army Ray and Joan Kroc Corps Community Center Chicago, Chicago |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.