Home › Small Cell Lung Cancer › NCT07175077
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
RecruitingObservational study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC). • Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease. * Patient also must not have a history of brain metastases or leptomeningeal disease. * Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T). * Patient must be ≥ 18 years of age. * Patient must have ECOG Performance Status of 0-2 * Patients must be able to tolerate the 7T MRI Exclusion Criteria: * Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies. * Patient must not have a contraindication to gadolinium contrast administration during MR imaging. * Patient must not have other metastatic malignancies requiring current active treatment. * Pregnant patients are excluded. Pregnancy status will be confirmed verbally.
About the study
Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.
What is being tested
- 7t MRI (device)
Sponsor: University of Missouri-Columbia · Participants: 20 · Started: Nov 1, 2025
Contact the study team
- Brooke McDaniel · Phone: 573-884-7488
Official record on ClinicalTrials.gov — NCT07175077
Locations in the U.S.
| Missouri | University of Missouri, Columbia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.