Home › Pain After Surgery › NCT07200544
Meloxicam in Mohs Micrographic Surgery
Meloxicam for Postoperative Pain in Mohs Micrographic Surgery
Who can join
Ages 18 to 110 · All sexes
Full eligibility criteria
Inclusion Criteria: * All adult patients who consents to the study and are undergoing Mohs micrographic surgery at the University of Oklahoma. Exclusion Criteria: * Women who are pregnant, suspected to be pregnant, or planning to become pregnant during the study period will be excluded from participation. * Chronic liver disease (chronic hepatitis, acute hepatitis, cirrhosis, NASH, NAFLD, alcoholic liver disease, hemochromatosis, Wilson's disease) * Chronic kidney disease stage III or greater, * Aspirin-sensitive asthma * History of chronic NSAID use * Patients vulnerable to drug interactions * GI bleeds * Peptic ulcers * Non-English speakers
About the study
The goal of this clinical trial is to explore alternative methods of postoperative pain control in Mohs micrographic surgery. The main aims are:
* To provide more information to the Mohs surgery community regarding postoperative pain control. * Reducing pain improves the overall comfort and well-being of patients, leading to a better post-operative experience. * To provide patients with an alternative and potentially superior NSAID for pain control (compared to standard-of-care ibuprofen).
Researchers will compare 1) a single of dose Meloxicam 7.5 mg, followed by acetaminophen 500 mg; 2) a single dose of Meloxicam 15 mg, followed by acetaminophen 500 mg; 3) a single dose of acetaminophen 500 mg, followed by alternating ibuprofen 200 mg and acetaminophen 500 mg to see which better moderate pain control and patient satisfaction.
Participants will be asked to complete pain and patient satisfaction surveys.
What is being tested
- Meloxicam 7.5 mg (drug)
- Meloxicam 15 mg (drug)
- Acetaminophen 500mg (drug)
Sponsor: University of Oklahoma · Participants: 300 · Started: Oct 15, 2025
Contact the study team
- Chase Pitchford, MD · Phone: 405-271-6110
- Landon Hendrickson, MD · Phone: 405-271-6110
Official record on ClinicalTrials.gov — NCT07200544
Locations in the U.S.
| Oklahoma | University of Oklahoma Health Sciences Center, Oklahoma City |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.