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Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

Recruiting

Who can join

Ages 60 to 90 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Ages 60 to 90 years old
* No prior diagnosis of dementia
* Currently hospitalized with cognitive diagnosis, including but no limited to; delirium, encephalopathy, etc. thought to be secondary to a toxic/metabolic state

Exclusion Criteria:

* Age under 60 years
* Prior diagnosis of dementing illness or other organic etiology to cognitive impairment

About the study

The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such as delirium or encephalopathy), will result in an earlier diagnosis of underlying Alzheimer's disease.

* Will this blood test have the ability to distinguish between Alzheimer's disease and other causes of cognitive impairment in the inpatient setting? * Neurology Clinic will complete a 6-month post-hospitalization follow up with patients who have had the Quest AD-Detect Alzheimer's Disease blood test completed while they were inpatient to discuss the risk assessment portfolio

What is being tested

Sponsor: Covenant Health, US · Participants: 30 · Started: Jun 10, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07222280

Locations in the U.S.

TennesseeCumberland Medical Center, Crossville
Roane Medical Center, Harriman
Fort Sanders Regional Medical Center, Knoxville
Fort Loudon Medical Center, Lenoir City
Methodist Medical Center, Oak Ridge
LeConte Medical Center, Sevierville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.