Home › Soft Tissue Sarcoma › NCT07227961
Activation Sarcoma: PROMIS and Mobility Evaluation in Sarcoma Patients
Patient-Reported Outcomes and Smartphone-Derived Mobility After Bone and Soft Tissue Sarcoma Surgery: A Multicentre Prospective Cohort Study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of bone sarcoma, soft tissue sarcoma, or giant cell tumor of bone * Tumors located in the pelvis, lower extremities, or upper extremities * Primary or recurrent disease * Undergoing operative tumor resection, including limb salvage surgery and amputation * Has an iPhone or Android smartphone * Speaks English Exclusion Criteria: * Metastatic bone tumor * Diagnosis of atypical lipomatous tumor * Diagnosis of dermatofibrosarcoma protuberans * Currently pregnant or planning pregnancy within 6 months * Unwilling or unable to attend follow-up evaluations * Cognitive or communication barriers that impede completion of questionnaires
About the study
Sarcoma is a rare form of bone and soft tissue cancer, making up about 1% of all adult cancers. Management typically involves radiation therapy, chemotherapy, and surgical resection. Surgery is central to the treatment of bone and soft tissue sarcoma, yet post-surgical recovery is difficult to measure because of disease rarity, multiple different tumor types, and treatment variation. Therefore, the overall goal of the study is to use patient reported outcome measures and mobility data to define recovery trajectories in sarcoma patients undergoing surgery, and to evaluate a novel smartphone application (app) entailed Activation Health for collecting these data.
Participants will download the Activation Health app on their smartphone. A demographics survey and multiple patient reported outcome measures will be administered remotely through the Activation Health app. Surveys will be completed preoperatively and at 6 weeks, 12 weeks, 6 months 12 months, 16 months, 20 months, and 24 months postoperatively. Additionally, the app will passively track mobility metrics such as daily step count, stairs climbed, and gait parameters throughout the study period. At the end of study participation, an additional surveys will be administered assess participant phone use habits and app function.
What is being tested
- Surgery (procedure)
Sponsor: University of Calgary · Participants: 800 · Started: Jul 1, 2025
Contact the study team
Official record on ClinicalTrials.gov — NCT07227961
Locations in the U.S.
| Arizona | Mayo Clinic, Phoenix (Not yet recruiting) |
| Minnesota | Mayo Clinic, Rochester (Not yet recruiting) |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.