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The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Who can join

Ages 35 to 79 · All sexes

Inclusion Criteria:

* RA diagnosed by a rheumatologist
* Age 40- 79
* ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking

Exclusion Criteria:

* Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
* Patients with diabetes mellitus
* Pregnancy

About the study

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

What is being tested

• high sensitivity cardiac troponin (diagnostic test)

Sponsor: Brigham and Women's Hospital · Participants: 120 · Started: Sep 4, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT07315997

Locations in the U.S.

Conditions

• Rheumatoid Arthritis
• Atherosclerosis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.