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Atherosclerosis clinical trials recruiting in the U.S.
38 studies for Atherosclerosis are recruiting participants at sites across the United States.
Atherosclerosis is hardening and narrowing of the arteries caused by the buildup of a fatty substance called plaque. Learn about the risks and prevention.
Cities with the most studies
- Boston, MA9 studies
- Houston, TX7 studies
- Washington, DC7 studies
- Durham, NC6 studies
- Hialeah, FL6 studies
- San Diego, CA5 studies
- Santa Monica, CA5 studies
- Minneapolis, MN5 studies
- Omaha, NE5 studies
- Dallas, TX5 studies
- Memphis, TN5 studies
- Tucson, AZ5 studies
- Los Angeles, CA5 studies
- Las Vegas, NV5 studies
- Orlando, FL5 studies
- Arlington, VA5 studies
- Richmond, VA4 studies
- Phoenix, AZ4 studies
- Miami, FL4 studies
- Aurora, CO4 studies
- Baltimore, MD4 studies
- New York City, NY4 studies
- Kirkland, WA4 studies
- Torrance, CA4 studies
- Meridian, ID4 studies
- Pittsburgh, PA4 studies
- The Woodlands, TX4 studies
- Cincinnati, OH4 studies
- Huntsville, AL4 studies
- Philadelphia, PA4 studies
- Indianapolis, IN4 studies
- St. Louis, MO4 studies
- Grand Prairie, TX3 studies
- Roanoke, VA3 studies
- Charleston, SC3 studies
- Mountain View, CA3 studies
- Atlanta, GA3 studies
- Albuquerque, NM3 studies
- Kansas City, MO3 studies
- Salt Lake City, UT3 studies
By state
- Alabama6 studies
- Arizona5 studies
- California11 studies
- Colorado6 studies
- Connecticut5 studies
- Florida8 studies
- Georgia6 studies
- Idaho4 studies
- Illinois5 studies
- Indiana6 studies
- Iowa4 studies
- Kansas4 studies
- Kentucky4 studies
- Louisiana3 studies
- Maryland9 studies
- Massachusetts10 studies
- Michigan6 studies
- Minnesota5 studies
- Missouri7 studies
- Nebraska6 studies
- Nevada5 studies
- New Jersey3 studies
- New Mexico4 studies
- New York7 studies
- North Carolina9 studies
- Ohio6 studies
- Pennsylvania9 studies
- South Carolina5 studies
- Tennessee6 studies
- Texas9 studies
- Utah6 studies
- Virginia6 studies
- Washington4 studies
- West Virginia3 studies
- Wisconsin3 studies
Recently updated studies
Causes and Natural History of Dyslipidemias
RecruitingObservational study
Ages 2 to 100 · All sexes · Updated Nov 12, 2026 · NCT00353782A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Nov 10, 2026 · NCT07839936A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 5, 2026 · NCT07521007Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
RecruitingObservational studyHealthy volunteers welcome
Ages 1 to 100 · All sexes · Updated Nov 4, 2026 · NCT01143454A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Nov 4, 2026 · NCT07613294A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07448038Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
Recruiting
Ages 55 and older · All sexes · Updated Nov 2, 2026 · NCT07704918Pharmacogenomic Informed Statin Prescribing
Recruiting
Ages 40 to 75 · All sexes · Updated Nov 2, 2026 · NCT06568601Study of the Effect of Innate on the Inflammatory Response to Endotoxin
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 26, 2026 · NCT01143480Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06471036Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure
Recruiting
Ages 18 to 55 · All sexes · Updated Oct 9, 2026 · NCT06962488New Heart Imaging Techniques to Evaluate Possible Heart Disease
RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 7, 2026 · NCT01399385How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Oct 6, 2026 · NCT07121010Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Oct 5, 2026 · NCT03581318Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07594392Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07157774Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05485961Detecting Peripheral Artery Disease With the Pulse
RecruitingHealthy volunteers welcome
Ages 19 and older · All sexes · Updated Sep 17, 2026 · NCT07226193PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07800481A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
RecruitingObservational study
Ages 35 to 79 · All sexes · Updated Jul 14, 2026 · NCT07315997PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Recruiting
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT05994014Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
Recruiting
Ages 65 to 84 · All sexes · Updated Jun 8, 2026 · NCT05867381Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
RecruitingHealthy volunteers welcome
Ages 30 to 65 · All sexes · Updated Jun 3, 2026 · NCT04496947From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.