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Atherosclerosis clinical trials recruiting in the U.S.
41 studies for Atherosclerosis are recruiting participants at sites across the United States.
Atherosclerosis is hardening and narrowing of the arteries caused by the buildup of a fatty substance called plaque. Learn about the risks and prevention.
Cities with the most studies
- Boston, MA10 studies
- Houston, TX10 studies
- Washington, DC9 studies
- Hialeah, FL8 studies
- Arlington, VA8 studies
- Orlando, FL8 studies
- Dallas, TX7 studies
- Durham, NC7 studies
- Memphis, TN7 studies
- Las Vegas, NV7 studies
- Miami, FL7 studies
- Amarillo, TX6 studies
- The Woodlands, TX6 studies
- Los Angeles, CA6 studies
- Minneapolis, MN6 studies
- Santa Monica, CA6 studies
- Omaha, NE6 studies
- Philadelphia, PA6 studies
- San Diego, CA6 studies
- Baltimore, MD6 studies
- Torrance, CA5 studies
- Winston-Salem, NC5 studies
- Raleigh, NC5 studies
- St. Louis, MO5 studies
- Huntsville, AL5 studies
- Meridian, ID5 studies
- Cincinnati, OH5 studies
- Pittsburgh, PA5 studies
- San Antonio, TX5 studies
- Tucson, AZ5 studies
- Phoenix, AZ5 studies
- Richmond, VA5 studies
- Tampa, FL5 studies
- Hollywood, FL5 studies
- Charlotte, NC5 studies
- Alexandria, VA5 studies
- Jacksonville, FL5 studies
- Aurora, CO4 studies
- Harrisburg, PA4 studies
- Atlanta, GA4 studies
By state
- Alabama8 studies
- Arizona6 studies
- Arkansas3 studies
- California14 studies
- Colorado6 studies
- Connecticut5 studies
- Florida11 studies
- Georgia8 studies
- Idaho5 studies
- Illinois8 studies
- Indiana8 studies
- Iowa5 studies
- Kansas5 studies
- Kentucky4 studies
- Louisiana6 studies
- Maryland12 studies
- Massachusetts11 studies
- Michigan7 studies
- Minnesota6 studies
- Mississippi4 studies
- Missouri8 studies
- Nebraska7 studies
- Nevada7 studies
- New Jersey6 studies
- New Mexico4 studies
- New York9 studies
- North Carolina12 studies
- Ohio8 studies
- Pennsylvania11 studies
- Rhode Island3 studies
- South Carolina6 studies
- South Dakota3 studies
- Tennessee9 studies
- Texas11 studies
- Utah8 studies
- Virginia9 studies
- Washington6 studies
- West Virginia4 studies
- Wisconsin4 studies
Recently updated studies
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07448038Causes and Natural History of Dyslipidemias
RecruitingObservational study
Ages 2 to 100 · All sexes · Updated Sep 29, 2026 · NCT00353782New Heart Imaging Techniques to Evaluate Possible Heart Disease
RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT01399385Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07157774Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07594392A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07521007A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
RecruitingObservational studyHealthy volunteers welcome
Ages 1 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143454Study of the Effect of Innate on the Inflammatory Response to Endotoxin
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143480Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05485961Detecting Peripheral Artery Disease With the Pulse
RecruitingHealthy volunteers welcome
Ages 19 and older · All sexes · Updated Sep 17, 2026 · NCT07226193Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Sep 8, 2026 · NCT03581318PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07800481A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Aug 7, 2026 · NCT06813911Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
Recruiting
Ages 55 and older · All sexes · Updated Aug 7, 2026 · NCT07704918Pelacarsen Roll-over Extension Program
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06875973Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06471036The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
RecruitingObservational study
Ages 35 to 79 · All sexes · Updated Jul 14, 2026 · NCT07315997PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Recruiting
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT05994014Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
Recruiting
Ages 65 to 84 · All sexes · Updated Jun 8, 2026 · NCT05867381Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
RecruitingHealthy volunteers welcome
Ages 30 to 65 · All sexes · Updated Jun 3, 2026 · NCT04496947High Protein Diet and Atherosclerosis
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated May 11, 2026 · NCT05235464From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.