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Atherosclerosis clinical trials recruiting in the U.S.

41 studies for Atherosclerosis are recruiting participants at sites across the United States.

Atherosclerosis is hardening and narrowing of the arteries caused by the buildup of a fatty substance called plaque. Learn about the risks and prevention.

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Recently updated studies

Causes and Natural History of Dyslipidemias

RecruitingObservational study
Ages 2 to 100 · All sexes · Updated Sep 29, 2026 · NCT00353782

New Heart Imaging Techniques to Evaluate Possible Heart Disease

RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT01399385

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07157774

Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07594392

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07521007

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

RecruitingObservational studyHealthy volunteers welcome
Ages 1 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143454

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143480

Detecting Peripheral Artery Disease With the Pulse

RecruitingHealthy volunteers welcome
Ages 19 and older · All sexes · Updated Sep 17, 2026 · NCT07226193

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Sep 8, 2026 · NCT03581318

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07800481

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

Recruiting
Ages 55 and older · All sexes · Updated Aug 7, 2026 · NCT07704918

Pelacarsen Roll-over Extension Program

RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06875973

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

RecruitingObservational study
Ages 35 to 79 · All sexes · Updated Jul 14, 2026 · NCT07315997

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

Recruiting
Ages 65 to 84 · All sexes · Updated Jun 8, 2026 · NCT05867381

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

RecruitingHealthy volunteers welcome
Ages 30 to 65 · All sexes · Updated Jun 3, 2026 · NCT04496947

High Protein Diet and Atherosclerosis

RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated May 11, 2026 · NCT05235464

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.