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HIV Suicide Prevention With AI-DBT

Recruiting

Piloting AI-Delivered Dialectical Behavioral Therapy for Suicide Prevention in Older Patients Living With HIV

Who can join

Ages 50 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Aged 50+
* evidence of suicide risk as defined by at least one of the following: PHQ-9 suicide item \> 0, Ask Suicide Questions (ASQ, an NIMH-supported suicide risk screener with a version tailored for primary care) \> 0, expression of suicidal thoughts to the provider during appointment, a suicide attempt in the past year, or PHQ-9 total score ≥ 8,
* ability to read and communicate fluently in English or Spanish
* not at imminent risk for suicide (does not have significant intent to die within 48 hours)
* has a smartphone capable of texting and accessing the internet.

Exclusion Criteria:

* deemed clinically inappropriate to participate because of severe psychosis, severe substance use, or severe cognitive deficits that would interfere with their comprehending study and intervention material.

About the study

One in four older persons living with HIV/AIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population. Currently, there are no behavioral interventions that specifically address suicide prevention for older PLWHA, despite their unique biopsychosocial and structural risk factors. Through this work, investigators will adapt Dialectical Behavior Therapy, an evidence-based intervention for suicide prevention, for patients with PLWHA to be delivered by an AI-powered conversational Agent developed by our industry partner, Empower Health. Investigators will then pilot test the feasibility, usability, acceptability and preliminary efficacy to improve self-efficacy to manage negative emotions in n=50 older adults living with HIV/AIDS.

What is being tested

Sponsor: Rutgers, The State University of New Jersey · Participants: 50 · Started: Jan 7, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07339189

Locations in the U.S.

New JerseyNew Jersey Community Research Initiative, Newark
RWJB Infectious Disease, Newark (Not yet recruiting)

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.