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Adapting RDAD for DS

Recruiting

Adapting the RDAD Intervention for Individuals With Down Syndrome Phase 3- Pilot Test

Who can join

All ages · All sexes

Full eligibility criteria
Inclusion Criteria - Adults with Down syndrome:

* Age \>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \~31 in adults with DS.
* Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.
* Living at home or in a supported living environment with a parent/caregiver who agrees to serve as a study partner.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Adults with Down syndrome:

* Unable to participate in moderate-to-vigorous physical activity.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

Inclusion Criteria - Caregivers

* Age ≥18 yrs.
* Reports being a primary caregiver of an adult with DS.
* English speaking.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Caregivers

* Unable to participate in moderate PA, i.e., brisk walking.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

About the study

The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.

What is being tested

Sponsor: University of Kansas Medical Center · Participants: 40 · Started: Mar 31, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07425769

Locations in the U.S.

KansasUniversity of Kansas Medical Center, Kansas City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.