Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

Recruiting

A Community-Engaged Approach to Culturally Adapting an Intervention to Increase Uptake of Genetic Testing Among African American Cancer Survivors

Who can join

Ages 20 to 79 · All sexes

Full eligibility criteria

Inclusion Criteria:

* Participants enrolled in Detroit Research on Cancer Survivors (Detroit ROCS)
* Diagnosis of Primary Breast, prostate, or colorectal cancer on or after 1/1/2013
* have received or currently receiving care at Karmanos Cancer Institute
* meet one or more of the National Comprehensive Cancer Network (NCCN) guidelines for cancer genetic testing as described below

Female breast

1. personal diagnosis at age ≤50
2. personal history of the triple-negative subtype
3. at least 1 close (first- or second-degree) relative diagnosed with breast cancer at age \<50
4. at least 1 close relative diagnosed with ovarian cancer
5. 2+ close relatives diagnosed with breast or prostate cancer
6. age \<50 AND another primary breast cancer at any age
7. 2+ primary breast cancers at any age

OR Prostate

1. personal history of high-risk or very high-risk prostate cancer
2. personal history of regional or metastatic prostate cancer
3. personal history of less than high-risk prostate cancer with a suggestive family history (i.e., father or brother or multiple relatives with prostate cancer diagnosed at age \<60; at least 1 relative with breast, ovarian, or pancreatic cancer; or at least 1 relative with colorectal, ovarian, pancreatic, or kidney cancer)

OR Colorectal

1. personal diagnosis at age ≤50
2. at least 1 close relative diagnosed with HNPCC at age \<50
3. at least 2 close relatives diagnosed with an HNPCC cancer at any age
4. colorectal and \>=1 primary endometrial, ovarian, gastric, pancreatic, or prostate

Exclusion Criteria:

* Previous genetic counseling and/or testing

About the study

The goal of this clinical trial is to culturally adapt an educational genetic counseling intervention to increase the uptake in genetic counseling and testing among African Americans at risk for heredity cancers. With the help of community stakeholders and clinical genetic professionals the investigators will:

* adapt and refine a culturally relevant online educational genetic counseling program for at-risk African Americans * Test the effects of the educational program * collaborate with community leaders and clinical genetic professionals to translate study findings, develop a road map for dissemination to the community, and identify barriers to prepare for future trials.

Participants from Detroit Research on Cancer Survivor group will be offered enrollment. Once consent is obtained, questionnaires will be completed before an online genetic counselling intervention immediately after, and at 3 months

What is being tested

Culturally adapted Online Genetic Counseling and Testing Information (behavioral)

Sponsor: Barbara Ann Karmanos Cancer Institute · Participants: 85 · Started: Apr 18, 2026

Contact the study team

Jasminder Phalore, MPH · Phone: 313-576-9735

Official record on ClinicalTrials.gov — NCT07436078

Locations in the U.S.

Michigan

Karmanos Cancer Institute, Detroit

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.