Post-op Prednisone and Glucose Monitoring in TKA

RecruitingPhase 4

Postoperative Prednisone Regimen in TKA and Its Effect on Continuous Glucose Levels

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

* MUST BE CONTACTED BY THE STUDY TEAM TO BE PART OF THE STUDY. No applications taken
* Undergoing Primary Unicompartmental Knee Arthroplasty or Total Hip Arthroplasty
* Age 18 and above
* Patient at Columbia University Irving Medical Center and be undergoing planned surgery by Dr. Roshan P. Shah

Exclusion Criteria:

* Steroid therapy
* Narcotic use within past 3 months
* History of corticosteroid intolerance
* Pregnancy
* Uncontrolled diabetes
* Doesn't own smart phone

Drop Criteria:

\- 2nd dose of IV dexamethasone

About the study

This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.

What is being tested

Prednisone (drug)
Continuous Glucose Monitor (device)
InkWell Health Tattoos (other)

Sponsor: Columbia University · Participants: 104 · Started: Jun 22, 2026

Contact the study team

Jacqueline Lenahan · Phone: (212) 305-8193

Official record on ClinicalTrials.gov — NCT07630896

Locations in the U.S.

New York

Columbia University Irving Medical Center, New York

Conditions

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.