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Osteoarthritis clinical trials recruiting in the U.S.
68 studies for Osteoarthritis are recruiting participants at sites across the United States.
Osteoarthritis is the most common form of arthritis. It usually affects your hands, knees, hips, or spine. Learn about treatment and management.
Cities with the most studies
- New York City, NY9 studies
- Chicago, IL8 studies
- Salt Lake City, UT5 studies
- Philadelphia, PA5 studies
- Charlotte, NC5 studies
- Tampa, FL5 studies
- Birmingham, AL4 studies
- Orlando, FL4 studies
- El Cajon, CA4 studies
- New Orleans, LA4 studies
- Houston, TX4 studies
- Atlanta, GA4 studies
- Gainesville, FL4 studies
- Tucson, AZ3 studies
- Ann Arbor, MI3 studies
- Troy, MI3 studies
- San Antonio, TX3 studies
- Dallas, TX3 studies
By state
- Alabama5 studies
- Arizona8 studies
- California9 studies
- Colorado8 studies
- Florida18 studies
- Georgia4 studies
- Illinois10 studies
- Indiana4 studies
- Kentucky4 studies
- Louisiana5 studies
- Massachusetts5 studies
- Michigan7 studies
- New York13 studies
- North Carolina10 studies
- Ohio6 studies
- Oregon3 studies
- Pennsylvania14 studies
- South Carolina4 studies
- Tennessee5 studies
- Texas6 studies
- Utah6 studies
- Virginia3 studies
Recently updated studies
A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07919678Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Nov 5, 2026 · NCT07339111Preoperative Music Intervention for Anxiety in Hip and Knee Arthroplasty
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07845695Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07353931EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))
Recruiting
Ages 21 and older · All sexes · Updated Nov 4, 2026 · NCT06631638A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07915609Oral Nutritional Optimization in Total Joint Arthroplasty
Recruiting
Ages 55 and older · All sexes · Updated Oct 30, 2026 · NCT04210284Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Oct 30, 2026 · NCT06859164Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 30, 2026 · NCT06965452Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA
RecruitingPhase 4
Ages 18 to 89 · All sexes · Updated Oct 28, 2026 · NCT07430085SMR Stemless Reverse vs SMR Reverse Shoulder System
Recruiting
Ages 22 and older · All sexes · Updated Oct 28, 2026 · NCT04697004Daily Knee Sleeve Use Versus No Use in Older Adults With Chronic Knee Pain
Recruiting
Ages 50 to 64 · All sexes · Updated Oct 27, 2026 · NCT07674901A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients (MOTION-P)
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 16, 2026 · NCT07219771Z1 Hip System: Post-Market Clinical Follow Up Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07104279Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for OA
RecruitingPhase 1
All ages · All sexes · Updated Oct 16, 2026 · NCT05147675Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis
RecruitingPhase 2
Ages 64 and older · All sexes · Updated Oct 13, 2026 · NCT07580716MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
Recruiting
Ages 18 to 60 · All sexes · Updated Oct 6, 2026 · NCT07332182Expanding Exercise Programming for Veterans Through Telehealth
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05666167Post-op Prednisone and Glucose Monitoring in TKA
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07630896Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Sep 30, 2026 · NCT07673328Low Dose Radiotherapy for Osteoarthritis
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07715188ARVIS TKA vs Conventional TKA
Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06663384Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
Recruiting
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07804446Ketorolac in Upper Extremity Tendinopathy and Arthropathy
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT05292339Clinical Orthopaedic Data Bank (Acute and Chronic)
RecruitingObservational study
All ages · All sexes · Updated Sep 3, 2026 · NCT00411060From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.