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Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy

Recruiting

Hydration Intervention to Address Dehydration Associated With Use of GLP-1 Based Medications

Who can join

Ages 18 to 60 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adults aged 18-60
* Recently prescribed a GLP-1RA (within one week of prescription)
* Fluent in English
* Willing to complete the study protocol

Exclusion Criteria:

* Children and adults \> 60 years of age
* Those not taking a GLP-1RA
* Those who have been on a GLP-1RA longer than one week
* Not fluent in English
* Those who are pregnant or planning on becoming pregnant during the duration of the study
* Unwilling to comply with study protocol
* People with cardiac implants

About the study

This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy. Investigators aim to increase hydration to potentially decrease side effect severity, amount of side effects, and drug discontinuation associated with GLP - 1 RA therapy. The investigators are piloting to assess feasibility and preliminary efficacy of the intervention through examining participant retention, participant feedback, researcher and participant adherence to protocols, impact on hydration biomarkers, and participant reported GLP - 1 RA side effects.

What is being tested

Sponsor: State University of New York at Buffalo · Participants: 30 · Started: Jun 15, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07641361

Locations in the U.S.

New YorkState University of New York at Buffalo, South Campus, Buffalo

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.