How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants

Recruiting

Oxygen Delivery in CPAP and Its Relationship With Regional Lung Ventilation in Preterm Infants

Who can join

All ages · All sexes

Full eligibility criteria

Inclusion Criteria:

* Gestational age at birth must be less than 35 weeks of completed gestation as documented in the subject's initial history and physical
* The infant must be stable while receiving nasal CPAP at any pressure level at the time of study
* The infant must be receiving 22-40% at the time of the study

Exclusion Criteria:

* Oxygen requirements greater than 40% at time of enrollment
* currently receiving invasive ventilation or not requiring ventilatory support
* Major congenital anomalies of the heart and/or lungs

About the study

With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP). To gain more information on how much oxygen is actually delivered to the baby from the nCPAP machine.

What is being tested

Effective oxygen delivery and lung expansion measurement (device)

Sponsor: University of Arkansas · Participants: 10 · Started: Apr 15, 2026

Contact the study team

Nicholas A Rowley, MD · Phone: 940-230-5002

Official record on ClinicalTrials.gov — NCT07674953

Locations in the U.S.

Arkansas

University of Arkansas for Medical Sciences, Little Rock (Not yet recruiting)
University of Arkansas for Medical Sciences, Little Rock

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.