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Respiratory Distress Syndrome clinical trials recruiting in the U.S.

32 studies for Respiratory Distress Syndrome are recruiting participants at sites across the United States.

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Recently updated studies

Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 16, 2026 · NCT07449572

Comparing Surfactant Administration Through Supraglottic Airway and Thin Catheter for Preterm Infants

Recruiting
0 Hours – 72 Hours · All sexes · Updated Sep 16, 2026 · NCT07030270

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT05947955

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05624450

The ARISE Study - Use of Vertical Positioning

Recruiting
Ages 18 to 80 · All sexes · Updated Aug 27, 2026 · NCT07025421

Vascular ARDS Recruitment After Inhaled Nitric Oxide

Recruiting
Ages 18 to 80 · All sexes · Updated Aug 18, 2026 · NCT05801224

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

RecruitingPhase 3
1 Hour – 24 Hours · All sexes · Updated Aug 6, 2026 · NCT06776783

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06701682

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06703073

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06701656

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06701669

Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT06513949

How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants

Recruiting
All ages · All sexes · Updated Jun 30, 2026 · NCT07674953

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06066502

A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)

RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Jun 23, 2026 · NCT05795465

Pharmacokinetics and Placental Transfer of Caffeine

RecruitingPhase 1
Ages 18 and older · Women · Updated Jun 4, 2026 · NCT07570121

Ventilator Pressure and Optimization of Compliance and Hemodynamics

Recruiting
7 Days – 30 Days · All sexes · Updated May 11, 2026 · NCT06512935

Breathing Patterns in Infants Before and After Extubation

RecruitingObservational studyHealthy volunteers welcome
0 Days – 6 Months · All sexes · Updated Apr 21, 2026 · NCT07542301

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Feb 23, 2026 · NCT05354141

The APS Phenotyping Study

RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT06521502

Macrophage Programing in Acute Lung Injury: MiniBAL

Recruiting
Ages 18 to 99 · All sexes · Updated Feb 6, 2026 · NCT05767671

Forced Oscillometry in Infants With Bronchopulmonary Dysplasia

RecruitingObservational study
All ages · All sexes · Updated Jan 21, 2026 · NCT04270045

Non Inferiority Trial Investigating Surfactants Administered Via MIST

RecruitingPhase 4
48 Hours · All sexes · Updated Aug 7, 2025 · NCT06074380

Prophylactic Minimally Invasive Surfactant Evaluation

RecruitingPhase 4Healthy volunteers welcome
15 Minutes · All sexes · Updated Aug 7, 2025 · NCT06007547

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

RecruitingObservational study
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.