Non-nutritive Sweeteners in Inflammatory Bowel Disease

Inclusion Criteria:

* Age range from: 18 to 70 years.
* Male or female.
* Documented diagnosis of Crohns disease. CD outpatients in remission; Harvey Bradshaw- index in remission (\<6 score).
* Capable of providing consent to participate.
* Able to complete daily surveys and take oral nutrition.
* Able to record meal intake.
* Healthy controls with no diagnosis of IBD or Irritable Bowel Syndrome (IBS).

Exclusion Criteria:

* Short bowel syndrome.
* Hospitalized patients.
* Individuals who lack consent capacity, including the mentally ill, prisoners, cognitively impaired participants, dementia patients.
* Known drug abuse.
* Known parasitic disease of the digestive system.
* Symptomatic intestinal stricture/narrowing.
* Presence of an ostomy.
* Known active malignancy.
* Antibiotic use within last 14 days.
* Well-founded doubt about the patients cooperation.
* Existing pregnancy or lactation.
* History of \<1 natural bowel movements per 3 consecutive days.
* Unable to access to technology that permits the daily completion of study related activities.
* Change in IBD medication within past 4 weeks.
* Body mass Index \<18 kg/m or ≥35 kg/m.
* Documented C.difficile colitis within four weeks of screening.
* Bariatric surgery
* Phenylketonuria