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A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

Who can join

Ages 20 to 79 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Healthy volunteers with normal eyes
* Visual acuity between +2 to -6 diopters

Exclusion Criteria:

* History of refractive or cataract surgery
* History of ocular disease
* Active non-ophthalmic systemic disease

About the study

The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.

Sponsor: Massachusetts General Hospital · Participants: 90 · Started: Aug 18, 2026

Contact the study team

• Soyeon (Selina) Ahn, PhD · Phone: 3396009736
• Seok-Hyun Yun, PhD · Phone: 6177688704

Official record on ClinicalTrials.gov — NCT07780890

Locations in the U.S.

Conditions

• Open-Angle Glaucoma
• Keratoconus
• Corneal Disorders

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.