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Head and Neck Cancer clinical trials in Pennsylvania
20 studies for Head and Neck Cancer are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Abramson Cancer Center of the University of Pennsylvania, Philadelphia
- University of Pittsburgh Medical Center, Pittsburgh
- WellSpan York Cancer Center, York
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
- Site #0103, Pittsburgh
- Site #0123, Pittsburgh
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990Distance-Based Exercise to Preserve Function and Prevent Disability
- UPMC Hillman Cancer Center at Butler Health System, Butler
- IRMC Cancer Center, Indiana
- UPMC Hillman Cancer Center - New Castle, New Castle
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884DESTINY-PANTUMOUR04
- Research Site, Philadelphia
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Pilot Study of Ultra-High Dose Rate (ConformalFLASH®), for Reirradiation of Carcinoma of the Head and Neck
- The University of Pennsylvania, Department of Radiation Oncology, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07644585A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
- UPMC, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
- University of Pennsylvania, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06125743Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
- Pennsylvania State University, Hershey
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05442957Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients
- UMPC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT07631650Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT05388773Lead-212 PSV359 Therapy for Patients With Solid Tumors
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations
- Fox Chase Cancer Center, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06030011Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema
- University of Pennsylvania Abramson Cancer Center, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06837480A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
- GSK Investigational Site, Philadelphia
- GSK Investigational Site, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT07501650The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
- Allegheny Health Network, Pittsburgh
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Cancer Care Associates of York (site 206), York
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingObservational study
All ages · All sexes · Updated Aug 15, 2025 · NCT05406167From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.