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Head and Neck Squamous Cell Carcinoma clinical trials in Tyler, TX

6 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Tyler (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #70, Tyler
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • UT Health East Texas HOPE Cancer Center, Tyler
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC

RecruitingPhase 2
  • Site US074, Tyler
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07807163

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • The University of Texas Health Science Center at Tyler, Tyler
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology, Tyler
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • UT Health East Texas HOPE Cancer Center, Tyler
  • UT Health East Texas Hope Cancer Center, Tyler
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Tyler

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.