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Breast Cancer clinical trials in Richmond, VA

26 studies for Breast Cancer are looking for participants at sites in and around Richmond (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

RecruitingPhase 3
  • Bon Secours Virginia Health System, Midlothian · 11 mi away
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Bon Secours Richmond Community Hospital, Richmond
  • Bon Secours Saint Mary's Hospital, Richmond
  • Bon Secours Cancer Institute at Reynolds Crossing, Richmond
  • and 3 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

RecruitingPhase 2
  • Virginia Cancer Institute, Richmond
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06369285

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Bon Secours Cancer Institute at St. Francis ( Site 0048), Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

RecruitingPhase 3
  • VCU Health Adult Outpatient Pavillion ( Site 0070), Richmond
  • Bon Secours St. Francis Medical Center-Oncology Research ( Site 0015), Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312176

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

Cardiovascular Health Education Via Virtual Reality for Breast Cancer Survivors Receiving Anthracyclines or Trastuzumab

Recruiting
  • Adult Outpatient Pavilion, Richmond
  • Cellular Immunotherapies and Transplant Department, Richmond
  • VCU Health at Stony Point, Richmond
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07426913

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • Bon Secours Cancer Institute at St. Mary's, Richmond
  • Bon Secours Cancer Institute at Memorial Regional, Mechanicsville · 6 mi away
  • Bon Secours St. Francis Medical Center, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Virginia Cancer Institute, Richmond
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

RecruitingPhase 3
  • Research Site, Midlothian · 11 mi away
Ages 18 to 130 · All sexes · Updated Sep 8, 2026 · NCT07647328

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Bon Secours Richmond Community Hospital, Richmond
  • Bon Secours Saint Mary's Hospital, Richmond
  • Bon Secours Cancer Institute at Reynolds Crossing, Richmond
  • and 4 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Bon Secours Richmond Community Hospital, Richmond
  • Bon Secours Saint Mary's Hospital, Richmond
  • Virginia Cancer Institute, Richmond
  • and 4 more
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

Recruiting
  • Virgina Community University Massey Comprehensive Cancer Center, Richmond
Ages 18 to 99 · Women · Updated Jul 17, 2026 · NCT05592938

Study to Evaluate the Feasibility of Twice Daily Use of Topical Azelaic Acid in Breast Cancer Patients Undergoing Radiation

RecruitingPhase 1
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06966388

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

RecruitingPhase 3
  • Virginia Commonwealth University, Richmond
Ages 65 and older · Women · Updated Jun 30, 2026 · NCT06507618

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Bon Secours St. Francis Medical Oncology Center, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

RecruitingPhase 3
  • Bon Secours Cancer Institute at Memorial Regional Medical Center, Mechanicsville · 6 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07062965

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Bon Secours Saint Mary's Hospital, Richmond
  • Bon Secours Cancer Institute at Reynolds Crossing, Richmond
  • Bon Secours Memorial Regional Medical Center, Mechanicsville · 6 mi away
  • and 1 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • VCU Massey Cancer Center at Stony Point, Richmond
  • Virginia Commonwealth University/Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients

RecruitingObservational study
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Mar 16, 2026 · NCT06610539

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

RecruitingObservational study
  • VCU Massey Comprehensive Cancer Center, Richmond
  • Bon Secours Cancer Institute at St. Francis, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421

ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy

RecruitingPhase 2
  • Virginia Commonwealth University, Richmond
Ages 45 to 79 · Women · Updated Nov 21, 2025 · NCT06185205

CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing

RecruitingHealthy volunteers welcome
  • Virginia Commonwealth University, Richmond
Ages 18 and older · Women · Updated Aug 28, 2025 · NCT05130606

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Richmond

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.